Calcium hydroxide and MTA



CALCIUM HYDROXIDE &
MTA (Mineral trioxide aggregate)

INTRODUCTION
Calcium cements are relatively weak cements
Calcium hydroxide is a white odorless powder which is mixed with water to a paste.
Due to their alkaline nature they serve as a protective barrier against irritants from certain restorations. pH 12.2
MECHANISM OF ACTION
Exact mechanism of action is still not known.
Calcium hydroxide maintains  a local state of alkalinity  that is necessary for bone/dentin formation .
High alkaline pH(11-13) causes neutralization of acids produced by microorganisms.

Biochemical Actions
Ca(OH)2 has the unique potential to induce mineralization, even in tissues which have not been programmed to mineralize.
The mechanism by which Ca(OH)2 initiates the reparative process is unclear.
It has been suggested that a rise in pH as a result of the free hydroxyl ions may initiate mineralization.
Ca(OH)2 may also act as a local buffer against the acidic reactions produced by the inflammatory process.
An alkalinic pH may also neutralize the lactic acid, secreted by osteoclasts, and this may help to prevent further destruction of mineralized tissue.
The high pH àmay activate alkaline phosphatase activity, which is postulated to play an important role in hard tissue formation.
Dentine bridge
A mineralized barrier usually produced following application of Ca(OH)2 to a vital pulp
This repair material appears to be a product of odontoblasts and Connective tissue cells.
Considerably reduces the permeability of exposed dentin for penetration of bacterial components towards the pulp.
 This may be due to 
         Coagulation of proteins in dentinal tubules
         Due to secondary dentin formation
         It has  an antibacterial effect
Calcium hydroxide has a strong antibacterial effect on the contaminated soft carious dentin.
Low grade irritation due to coagulative necrosis caused by calcium hydroxide leading to hard tissue differentiation in the pulp to calcify barrier formation.
AVAILABILITY
Powder form (mixed with distilled water)
Two paste system containing base and catalyst pastes in collapsible tubes.
 Light cured system Single paste in syringe form (pulpdent).
Light cured two paste system
Setting pastes
The therapeutic properties of the setting CaOH2 materials are related to their pH.

Strong effect:
Dycal (original formula)
Reocap
Procal
Medium effect:
Dycal (New formula)
Life
Renew
Reolit.
No effect:
M.P.C.
Hydrex
Cal-Mer- VII
Non setting pastes
Analar Ca(OH2) – H2O
Pulp dent methyl cellulose
Hypocal methyl cellulose
Reogan methyl cellulose
Visible light activated calcium hydroxide – Single paste system.
Calcium hydroxide
Barium sulphate
UDMA Resin
Camphoroquinone (photoinitiator)
   SLOW SETTING calcium hydroxide Pastes.
-mainly used as root Canal Sealer  materials 
Calcium hydroxide can be used as a sealer to coat  the pulp space and form a hermetic seal
   Ex – Calcibiotic sealer
VEHICLES
  When calcium hydroxide powder is mixed with a suitable vehicle a paste is formed.
Mainly three types of Vehicles are used
    Aqueous Vehicles – Water: Sterile
                                                                   Distilled
    Viscous  Vehicles  - Glycerine
                                                    Polyethyl glycol

    Oily vehicles       -   Olive Oil
                                                   Fatty acids.
                                                   Eugenol.
Commercial names : 
   Self cured : dycal, Life, Care, calcidor
            Light cured: Prisma VLC dycal
 
Thermal properties : 
If used in sufficiently thick layers, they provide some thermal insulation. However a thickness greater than 0.5mm is not recommended. Thermal protection should be provided with a separate base.
MANIPULATION
Simply powder is carried to the cavity. Little wetness in the cavity will be sufficient for calcium hydroxide to get adapted to the floor.

Calcium hydroxide is mixed with clean water and carried to the cavity as a paste.
Equal length of both the pastes are taken on paper pad and mixed to get a uniform color.  
                                        
Material is taken, carried to the cavity and light cured. As curing is done after adaptation, there is adequate time for use
MTA (mineral trioxide aggregate)
CONTENTS
Introduction
Development
Applications
Composition and type
Clinical technique
Advantages
Limitations

   MTA is a powder that consists of fine hydrophilic particles that set in the presence of moisture.
    Hydration of the powder results in a colloidal gel that solidifies to a hard structure.
Development
  Research in 1990s in Loma Linda University by Torabinejad and associates.
  First published by Torabinejad in 1993
  Introduced as root end filling material
  As furcation repair material by Pitt ford et al 1995
        COMPOSITION
MTA
(Portland cement 75%)
  Tricalcium Silicate
  Dicalcium Silicate
  Tricalcium Aluminate
  Tetracalcium Aluminoferrite
  Tricalcium oxide
  Bismuth Oxide – 20%
  Calcium Sulfate Dihydrate (gypsum) – 5%
Types
1.     Grey MTA
2.     White MTA
Commercial Availability
 
PRO ROOT MTA
MTA ANGELUS
Grey MTA
White MTA
MTA ANGELUS
80% Portland cement + 20 % bismuth oxide
No gypsum
Calcium chloride
       APPLICATIONS
        WHY MTA ???
Superior sealing ability
Better root end seal
Ability to set even in presence of blood or moisture
Low solubility
Low toxicity
Bactericidal
Stimulate cementogenesis and dentinogenesis
No mutagenicity
Aid in periodontal regeneration
Biological response in osteoblastic cells
Reduced treatment time and patient appointments compared to other materials
Properties
Micro leakage
Biocompatibility
Physical properties
Osteogenic potential
Antimicrobial properties
WHY LESS MICROLEAKAGE ?
  Fine Hydrophilic propertiesà absorbs water during hydration
  Expansion leading to superior adaptation 
    BIOCOMPATIBILITY
Biocompatibility
  Important property for clinical success
  Absence of cytotoxicity when contacted with fibroblasts and osteoblasts
  Less inflammation compared to calcium hydroxide
Physical Properties
  Initial PH 10.2 , Final PH 12.5
  Working time 5 minutes
  Initial Setting time 3 to 4 hrs
  Compressive strength at 24 hrs – 40 mpa
  21 days – 70 MPa
  Hydrophilic - sets in the presence of moisture
Osteogenic Potential
Calcium present in abundance in the cement
When contacted with moisture
Calcium released reacts with phosphate
Calcium phosphate acts as hydroxy apatite crystal
Induce biological response in Osteoblastic cells due to adhesion
  Cytokines increased like IL 4 and IL 10 or IL 1 alpha and IL 6
  Induces Alkaline Phosphotase production
  Acts as a scaffold for bone deposition
ANTI MICROBIAL
Release of hydroxyl ions
Increased PH
Unfavorable for bacterial growth
Manipulation
         Open single pouch
         Use entire contents of water ampule
         P:L  ratioà 3:1
         Gradual mixing with sterile water
         Hydrate all the powder
         Add 1 to 2 drops of sterile water, if too stiff
         Thick creamy consistency
         Cover with moistened gauze to extend the working time
MTA CARRIERS
MTA PLUGGERS
Uses
1.Vital pulp therapy
Direct pulp capping
Pulpotomy
2.Perforation management
Furcation
Lateral
Apical
3.Apexification & Apexogenesis
4.Retreatment
Internal resorption
External resorption
5.Surgical
Retrograde root end filling
OTHERS
Vertical fractures
Coronal plug for internal bleaching
Obturation
 PULP CAPPING
PULPAL REACTION

                                   
                                                                                   (alkalinity)
                                   
                                                                         
                                   
                                                                                                     
                                   
                                                                                       
                                   
                                                                                       
                                   
           PULPOTOMY
Success
  Induce hard tissue formation at faster rate
  Thicker dentin bridge, more frequent odontoblastic layer formation
  Greater ability to maintain integrity of pulp than calcium hydroxide
  Less inflammation
 
            PERFORATION
           MANAGEMENT
Radicular Perforation
 INTERNAL RESORPTION
Internal Resorption
APEXIFICATION
  SURGICAL USES
Root end filling
LIMITATIONS OF MTA
Setting time is more
Expensive
Radiopacity higher than dentin
Difficult handling
Thank you..!

Comments

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