Calcium hydroxide and MTA
CALCIUM HYDROXIDE & 
MTA (Mineral trioxide aggregate)
MTA (Mineral trioxide aggregate)
INTRODUCTION 
Calcium cements are relatively weak cements
Calcium hydroxide is a white odorless powder which is mixed
with water to a paste.
Due to their alkaline nature they serve as a protective
barrier against irritants from certain restorations. pH 12.2 
MECHANISM OF ACTION
Exact mechanism of action is still not known.
Calcium hydroxide maintains 
a local state of alkalinity  that
is necessary for bone/dentin formation . 
High alkaline pH(11-13) causes neutralization of acids
produced by microorganisms. 
Biochemical Actions
Ca(OH)2 has the unique potential to induce
mineralization, even in tissues which have not been programmed to mineralize.
The mechanism by which Ca(OH)2 initiates the
reparative process is unclear. 
It has been suggested that a rise in pH as a result of the free
hydroxyl ions may initiate mineralization. 
Ca(OH)2 may also act as a local buffer against the
acidic reactions produced by the inflammatory process. 
An alkalinic pH may also neutralize the lactic acid, secreted
by osteoclasts, and this may help to prevent further destruction of mineralized
tissue.
The high pH àmay activate
alkaline phosphatase activity, which is postulated to play an important role in
hard tissue formation.
Dentine bridge 
A mineralized barrier usually produced following application
of Ca(OH)2 to a vital pulp
This repair material appears to be a product of odontoblasts
and Connective tissue cells.
Considerably reduces the permeability of exposed dentin for
penetration of bacterial components towards the pulp.
 This may be due
to  
         Coagulation of
proteins in dentinal tubules 
         Due to
secondary dentin formation 
         It has  an antibacterial effect 
Calcium hydroxide has a strong antibacterial effect on the
contaminated soft carious dentin.
Low grade irritation due to coagulative necrosis caused by
calcium hydroxide leading to hard tissue differentiation in the pulp to calcify
barrier formation. 
AVAILABILITY 
Powder form (mixed with distilled water) 
Two paste system containing base and catalyst pastes in
collapsible tubes.
 Light cured system
Single paste in syringe form (pulpdent).
Light cured two paste system
Setting pastes
The therapeutic properties of the setting CaOH2 materials are
related to their pH. 
Strong effect: 
Dycal (original formula)
Reocap 
Procal 
Medium effect: 
Dycal (New formula)
Life 
Renew
Reolit.
No effect: 
M.P.C.
Hydrex 
Cal-Mer- VII
Non setting pastes 
Analar Ca(OH2) – H2O
Pulp dent methyl cellulose
Hypocal methyl cellulose
Reogan methyl cellulose
Visible light activated calcium hydroxide – Single paste
system. 
Calcium hydroxide
Barium sulphate 
UDMA Resin 
Camphoroquinone (photoinitiator) 
   SLOW SETTING calcium
hydroxide Pastes. 
-mainly used as root Canal Sealer  materials 
Calcium hydroxide can be used as a sealer to coat  the pulp space and form a hermetic seal 
   Ex – Calcibiotic
sealer
VEHICLES 
  When calcium
hydroxide powder is mixed with a suitable vehicle a paste is formed.
Mainly three types of Vehicles are used 
    Aqueous Vehicles –
Water: Sterile 
                                                                   Distilled 
    Viscous  Vehicles 
- Glycerine 
                                                    Polyethyl glycol 
    Oily vehicles       -  
Olive Oil 
                                                   Fatty acids. 
                                                   Eugenol. 
Commercial names :  
   Self cured : dycal,
Life, Care, calcidor 
            Light cured:
Prisma VLC dycal 
Thermal properties :  
If used in sufficiently thick layers, they provide some
thermal insulation. However a thickness greater than 0.5mm is not recommended.
Thermal protection should be provided with a separate base. 
MANIPULATION 
Simply powder is carried to the cavity. Little wetness in the
cavity will be sufficient for calcium hydroxide to get adapted to the floor.
Calcium hydroxide is mixed with clean water and carried to
the cavity as a paste.
Equal length of both the pastes are taken on paper pad and
mixed to get a uniform color.   
Material is taken, carried to the cavity and light cured. As
curing is done after adaptation, there is adequate time for use
MTA (mineral trioxide
aggregate)
CONTENTS
Introduction
Development
Applications
Composition and type
Clinical technique
Advantages 
Limitations
   MTA is a powder that
consists of fine hydrophilic particles that set in the presence of moisture. 
    Hydration of the
powder results in a colloidal gel that solidifies to a hard structure.
Development 
  Research in
1990s in Loma Linda University by Torabinejad and associates.
  First
published by Torabinejad in 1993 
  Introduced
as root end filling material
  As
furcation repair material by Pitt ford et al 1995
        COMPOSITION
MTA
(Portland cement 75%)
(Portland cement 75%)
  Tricalcium
Silicate
  Dicalcium
Silicate
  Tricalcium
Aluminate 
  Tetracalcium
Aluminoferrite 
  Tricalcium
oxide
  Bismuth
Oxide – 20%
  Calcium
Sulfate Dihydrate (gypsum) – 5%
Types
1.    
Grey MTA 
2.    
White MTA 
Commercial Availability
 
PRO ROOT MTA
MTA ANGELUS 
Grey MTA
White MTA
MTA ANGELUS 
80% Portland cement + 20 % bismuth oxide 
No gypsum 
Calcium chloride
       APPLICATIONS
        WHY MTA ??? 
Superior sealing ability
Better root end seal
Ability to set even in presence of blood or moisture
Low solubility
Low toxicity
Bactericidal
Stimulate cementogenesis and dentinogenesis 
No mutagenicity
Aid in periodontal regeneration
Biological response in osteoblastic cells 
Reduced treatment time and patient appointments compared to
other materials
Properties
Micro leakage
Biocompatibility
Physical properties
Osteogenic potential
Antimicrobial properties
WHY LESS MICROLEAKAGE ? 
  Fine
Hydrophilic propertiesà absorbs
water during hydration
  Expansion
leading to superior adaptation  
    BIOCOMPATIBILITY
Biocompatibility
  Important
property for clinical success
  Absence of
cytotoxicity when contacted with fibroblasts and osteoblasts
  Less inflammation
compared to calcium hydroxide 
Physical Properties
  Initial PH
10.2 , Final PH 12.5 
  Working
time 5 minutes
  Initial
Setting time 3 to 4 hrs 
  Compressive
strength at 24 hrs – 40 mpa 
  21 days –
70 MPa 
  Hydrophilic
- sets in the presence of moisture 
Osteogenic Potential 
Calcium present in abundance in the cement
When contacted with moisture 
Calcium released reacts with phosphate 
Calcium phosphate acts as hydroxy apatite crystal
Induce biological response in Osteoblastic cells due to adhesion
  Cytokines
increased like IL 4 and IL 10 or IL 1 alpha and IL 6 
  Induces
Alkaline Phosphotase production 
  Acts as a
scaffold for bone deposition
ANTI MICROBIAL 
Release of hydroxyl ions 
Increased PH
Unfavorable for bacterial growth
Manipulation
•        
Open single pouch
•        
Use entire contents of water ampule
•        
P:L  ratioà 3:1
•        
Gradual mixing with sterile water
•        
Hydrate all the powder
•        
Add 1 to 2 drops of sterile water, if too stiff
•        
Thick creamy consistency
•        
Cover with moistened gauze to extend the working time 
MTA CARRIERS
MTA PLUGGERS
Uses 
1.Vital pulp therapy
Direct pulp capping
Pulpotomy 
2.Perforation management
Furcation 
Lateral
Apical
3.Apexification & Apexogenesis 
4.Retreatment 
Internal resorption 
External resorption 
5.Surgical
Retrograde root end filling
OTHERS 
Vertical fractures 
Coronal plug for internal bleaching
Obturation 
 PULP CAPPING
PULPAL REACTION
                                                                                   ↓ (alkalinity)
                                                                      ↓    
                                                                                                   ↓  
                                                                                       ↓ 
                                                                                       ↓ 
           PULPOTOMY
Success
  Induce hard
tissue formation at faster rate
  Thicker
dentin bridge, more frequent odontoblastic layer formation
  Greater
ability to maintain integrity of pulp than calcium hydroxide 
  Less
inflammation 
            PERFORATION
           MANAGEMENT
Radicular Perforation
 INTERNAL RESORPTION
Internal Resorption 
APEXIFICATION
  SURGICAL
USES
Root end filling 
LIMITATIONS OF MTA
Setting time is more 
Expensive
Radiopacity higher than dentin 
Difficult handling 
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